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Can I read High seroprevalence of multiple high-risk human papillomavirus types among the general population of Bonaire, St. Eustatius and Saba, Caribbean Netherlands on EtoBox?
High seroprevalence of multiple high-risk human papillomavirus types among the general population of Bonaire, St. Eustatius and Saba, Caribbean Netherlands by Vos, Regnerus A.; Pasmans, Hella; Tymchenko, Liza; Janga-Jansen, Alcira V.A.; Baboe-Kalpoe, Sharda; Hulshof, Koen; de Melker, Hester E.; van der Klis, Fiona R.M. is a Medicine article available to read on EtoBox.
What is High seroprevalence of multiple high-risk human papillomavirus types among the general population of Bonaire, St. Eustatius and Saba, Caribbean Netherlands about?
## Background: Incidence and mortality of human papillomavirus (hpv)-related cancers differs geographically, with high rates in caribbean countries. seroepidemiological data provide information on lifetime cumulative hpv exposure and contributing risk factors, but has not been available yet for caribbean netherlands (cn), comprising the islands bonaire, st. eustatius and saba. therefore, a cross-sectional population-based serosurveillance study was performed in this (recently girls-only hpv-vaccinated) population in 2017. ## Methods: Blood samples from participants (n = 1,823, 0-90 years) were tested for seven high-risk (hr)-hpv-specific igg-antibodies using a vlp-based multiplex-immunoassay. risk factors for hpv-seropositivity were analysed among persons unvaccinated aged ≥ 15 years who ever had sex (n = 1,080). ## Results: Among unvaccinated individuals aged ≥ 15 years, overall seropositivity was high (34%), with over half of them being seropositive for ≥ 2 hr-hpv types, and hpv16 and 52 being most prevalent (13%). seroprevalence was substantial higher in unvaccinated women (51%) than men (18%), predominantly peaking in women aged 20-59 years, and was highest on st. eustatius (38
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- Author
- Vos, Regnerus A.; Pasmans, Hella; Tymchenko, Liza; Janga-Jansen, Alcira V.A.; Baboe-Kalpoe, Sharda; Hulshof, Koen; de Melker, Hester E.; van der Klis, Fiona R.M.
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV; ScienceOpen (ISSN 0264-410X)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)