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Exploring the Immune Response, Tolerance and Resistance in Proliferative Kidney Disease of Salmonids by Christyn Bailey; Nicole Strepparava; Thomas Wahli; Helmut Segner is a Immunology and Microbiology article available to read on EtoBox.

What is Exploring the Immune Response, Tolerance and Resistance in Proliferative Kidney Disease of Salmonids about?

Proliferative kidney disease (PKD) of salmonids is a disease of economic and environmental concern caused by the myxozoan parasite Tetracapsuloides bryosalmonae. Finer details of the immune repertoire during T. bryosalmonae infection have been elucidated in rainbow trout (Oncorhynchus mykiss). In contrast, there remain many unanswered questions regarding the immune response of the wild fish host in Europe, the brown trout (Salmo trutta) to this parasite. The first aim of this study is to examine the brown trout immune response to T. bryosalmonae and compare it with the published information on rainbow trout as two species that have undergone a different coevolution with the parasite. According to ecoimmunology terminology, infected organisms may manage infection by reducing the damage caused by parasites (tolerance) or by limiting parasite burden (resistance). The second aim of this study is to investigate tolerance/resistance patterns of these species during PKD infection. Our results suggest subtle differences in sequential aspects of the immune response and of immune genes that correlate with parasite intensity for the brown trout, in contrast to rainbow trout, in terms of the B

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Author

Christyn Bailey; Nicole Strepparava; Thomas Wahli; Helmut Segner

Published

2018

Language

EN

Field

Immunology and Microbiology (Life Sciences)