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What is PFOS and PFOSA Induce Cardiac Defects in Zebrafish about?

This study investigates the effects of perfluorooctane sulfonate (PFOS) and its precursor perfluorooctane sulfonamide (PFOSA) on cardiac development in zebrafish, revealing that both compounds induce cardiac defects through oxidative stress via different signaling pathways: PPARγ for PFOS and AHR for PFOSA. The exposure to these chemicals resulted in increased reactive oxygen species production, mitochondrial damage, and apoptosis in embryonic hearts. The findings suggest that maternal exposure to PFOS and

Author

akanniabdulmajeedolawale

Language

EN