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Can I read Durability of Partial Splenic Artery Embolization on Platelet Counts for Cancer Patients with Hypersplenism-related Thrombocytopenia on EtoBox?
Durability of Partial Splenic Artery Embolization on Platelet Counts for Cancer Patients with Hypersplenism-related Thrombocytopenia by Hill, Ashley; Elakkad, Ahmed; Kuban, Joshua; Sabir, Sharjeel; Odisio, Bruno; Huang, Steven Y.; Mahvash, Armeen; Miller, Ethan; Kroll, Michael H.; Overman, Michael; Tam, Alda L.; Gupta, Sanjay; Sheth, Rahul A. is a Medicine article available to read on EtoBox.
What is Durability of Partial Splenic Artery Embolization on Platelet Counts for Cancer Patients with Hypersplenism-related Thrombocytopenia about?
## Purpose: Partial splenic artery embolization (psae) has shown promise in increasing platelet counts in cancer patients with hypersplenism-related thrombocytopenia. the purpose of this study was to identify response predictors and to longitudinally evaluate psae efficacy and durability in a large cohort of cancer patients with hypersplenism-related thrombocytopenia. ## Methods: A single-institution, irb-approved, hipaa-compliant retrospective review of all psaes for thrombocytopenia between 2012 and 2015 was performed. patients were classified as complete responders (cr, no platelet value < 100 × 10/l following psae), partial responders (pr, initial increase in platelets but subsequent decrease in platelets 100 × 10/l following psae). ## Results: Of the 98 patients included in the study, 58 had cr (59%), 28 had pr (29%), and 12 patients had nr (12%). the percent splenic tissue embolized was significantly greater in the cr group compared to the pr group (p = 0.001). the percent volume of splenic tissue embolized was linearly correlated with the magnitude of platelet increase without a minimum threshold. at least one line of chemotherapy was successfully restarted in 97% of patie
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- Author
- Hill, Ashley; Elakkad, Ahmed; Kuban, Joshua; Sabir, Sharjeel; Odisio, Bruno; Huang, Steven Y.; Mahvash, Armeen; Miller, Ethan; Kroll, Michael H.; Overman, Michael; Tam, Alda L.; Gupta, Sanjay; Sheth, Rahul A.
- Publisher
- Springer-Verlag; Springer New York LLC; Springer Science and Business Media LLC (ISSN 2366-004X)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)