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Can I read Immuno-histological Observations Upon the Development of Reticulum Cell Sarcoma in the Mouse on EtoBox?
Immuno-histological Observations Upon the Development of Reticulum Cell Sarcoma in the Mouse by C. R. Taylor is a Medicine article available to read on EtoBox.
What is Immuno-histological Observations Upon the Development of Reticulum Cell Sarcoma in the Mouse about?
Detailed observations were made of the development of "reticulum cell sarcoma" in four strains of laboratory mice: SJL/J, NZB, PBA and (BALB/C X A)F1 hybrids injected with parental (BALB/C) spleen cells. Morphological evidence of a florid B cell immune response was present in all four strains, and was succeeded by a phase of atypical lymphoid hyperplasia, prior to the appearance of malignant neoplasms in lymph-nodes or spleen. These neoplasms correspond to descriptions of "reticulum cell sarcoma" of the mouse. The demonstration, by immunoperoxidase methods, of immunoglobulin within a proportion of these "malignant reticulum cells" reinforces the opinion, based on the morphological evidence of hyperplasia progressing to neoplasia, that the "reticulum cell sarcoma" of the mouse is B lymphocyte derived.
Who reads Immuno-histological Observations Upon the Development of Reticulum Cell Sarcoma in the Mouse?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- C. R. Taylor
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0022-3417)
- Published
- 1976
- Language
- EN
- Field
- Medicine (Health Sciences)