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Antenatal imaging and clinical outcome in congenital CMV infection: a field-wide systematic review and meta-analysis by Kyriakopoulou, Aikaterini; Serghiou, Stylianos; Dimopoulou, Dimitra; Arista, Ioli; Psaltopoulou, Theodora; Dinopoulos, Argyrios; Papaevangelou, Vassiliki is a Medicine article available to read on EtoBox.
What is Antenatal imaging and clinical outcome in congenital CMV infection: a field-wide systematic review and meta-analysis about?
## Objectives: Postnatal outcome in fetuses with congenital cytomegalovirus infection (ccmv) varies from asymptomatic infection to severe neurodevelopmental impairment. αntenatal biomarkers of long-term clinical outcome, have yet to be established. α systematic review and meta-analysis was performed to examine whether prenatal cerebral ultrasonography (us) and magnetic resonance imaging (mri) findings in ccmv fetuses may predict clinical outcome. ## Methods: Pubmed and the web of science were systematically searched to identify studies reporting on any prenatal us and/or mri imaging of fetuses with ccmv as well as their postnatal clinical outcome. all reported associations between imaging and postnatal clinical outcome were systematically extracted. where appropriate, the reported associations were quantitatively synthesized within bayesian random-effects meta-analyses. ## Results: A total of 1336 studies were screened to identify 26 eligible observational studies. overall, 4181 fetuses were studied, of which 1518 had been diagnosed with ccmv. all studies performed fetal us while in 14 (54%) mri was also performed. studies substantially varied in timing of fetal imaging, reporting
Who reads Antenatal imaging and clinical outcome in congenital CMV infection: a field-wide systematic review and meta-analysis?
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- Author
- Kyriakopoulou, Aikaterini; Serghiou, Stylianos; Dimopoulou, Dimitra; Arista, Ioli; Psaltopoulou, Theodora; Dinopoulos, Argyrios; Papaevangelou, Vassiliki
- Publisher
- Elsevier Science; Elsevier ; W. B. Saunders Co., Ltd.; Elsevier BV (ISSN 0163-4453)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)