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Sarcoidosis and Major Histocompatibility Complex Genes with Special Emphasis on BF F Subtypes by O. Finco; M. Martinetti; E. Dondi; M. Luisetti; L. Pasturenzi; M. Cuccia is a Medicine article available to read on EtoBox.

What is Sarcoidosis and Major Histocompatibility Complex Genes with Special Emphasis on BF F Subtypes about?

Frequencies for HLA class I and II histoglobulins and C4A, C4B, BF complement proteins were performed for 59 sarcoidosis patients. The DR5 allele was present in 55.9% of patients as compared to 31.5% of controls. We noticed that its increase was more relevant in males and in those with a poor prognosis. BF F allele was significantly over-represented in patients (29.09% vs. 19.15% of control), especially in women. Special emphasis was given to BF F subtyping, to define an association between a particular BF F subtype and patient's sex or disease outcome.

Who reads Sarcoidosis and Major Histocompatibility Complex Genes with Special Emphasis on BF F Subtypes?

Author

O. Finco; M. Martinetti; E. Dondi; M. Luisetti; L. Pasturenzi; M. Cuccia

Publisher

S. Karger AG; Karger AG (ISSN 1012-8204)

Published

1991

Language

EN

Field

Medicine (Life Sciences)