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Fungal Endophytes: a Source of Antibacterial and Antiparasitic Compounds by Romina Pacheco; Sergio Ortiz; Mohamed Haddad; Marieke Vansteelandt is a book available to read on EtoBox.

What is Fungal Endophytes: a Source of Antibacterial and Antiparasitic Compounds about?

According to the WHO, there are currently 20 diseases caused by bacteria, helminths, protozoa, or viruses considered as part of the neglected tropical diseases, including Chagas disease, human African trypanosomiasis, leishmaniasis, and many others. Individually, none of them represents a global priority, however, counted together, they affect approximately two billion people with a collective number of people affected equivalent to HIV/AIDS, tuberculosis, or malaria . In general, the arsenal of antimicrobial drugs is becoming very limited while the resistance development is rising against many of the main treatments. The problem of antibiotic resistance also involves natural environmental changes and proliferation of infections due to human activities. The absence of effective vaccines and the development of resistance to the current drugs situate these infections as major problems in endemic countries and highlight the need of novel molecules acting on new targets. ## Microbial natural products as sources of new drugs A significant number of compounds, including drugs and drug leads, are produced by microorganisms during the interaction with other microorganisms and with their en

Author

Romina Pacheco; Sergio Ortiz; Mohamed Haddad; Marieke Vansteelandt

Publisher

Elsevier

Published

2022

Language

EN