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Exosome‐derived differentiation antagonizing non‐protein coding RNA with risk of hepatitis C virus‐related hepatocellular carcinoma recurrence by Shu‐Chi Wang; Chia‐Yang Li; Wen‐Tsan Chang; Wei‐Chung Cheng; Chia‐Hung Yen; Wen‐Yu Tu; Zu‐Yau Lin; Ching‐Chih Lin; Ming‐Lun Yeh; Chung‐Feng Huang; Jee‐Fu Huang; Chia‐Yen Dai; Wan‐Long Chuang; Yao‐Li Chen; Ming‐Lung Yu is a Medicine article available to read on EtoBox.
What is Exosome‐derived differentiation antagonizing non‐protein coding RNA with risk of hepatitis C virus‐related hepatocellular carcinoma recurrence about?
## Background & aims: Differentiation antagonizing non-protein coding rna is associated with various types of neoplasms. hepatitis c virus-related hepatocellular carcinoma has a high risk of recurrence. here we determined the role of differentiation antagonizing non-protein coding rna in hepatitis c virus-related hepatocarcinogenesis and identified potential therapeutic targets and non-invasive prognostic markers for long-term outcome of hepatitis c virus-related hepatocellular carcinoma after surgical resection. ## Methods: Differentiation antagonizing non-protein coding rnas relevant to hepatitis c virus-related hepatocellular carcinoma were identified through comparative rna-sequencing of tumour and adjacent non-tumour (ant) tissues in a screening set, and were validated using real-time polymerase chain reaction. target long non-coding rnas (lncrnas) in tissues and serum exosomes were used to predict the recurrence of hepatitis c virus-related hepatocellular carcinoma after curative surgical resection in a large application cohort from 2005 to 2012. ## Results: We confirmed that differentiation antagonizing non-protein coding rna was upregulated following hepatitis c virus infec
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- Author
- Shu‐Chi Wang; Chia‐Yang Li; Wen‐Tsan Chang; Wei‐Chung Cheng; Chia‐Hung Yen; Wen‐Yu Tu; Zu‐Yau Lin; Ching‐Chih Lin; Ming‐Lun Yeh; Chung‐Feng Huang; Jee‐Fu Huang; Chia‐Yen Dai; Wan‐Long Chuang; Yao‐Li Chen; Ming‐Lung Yu
- Publisher
- Wiley
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)