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Drug-associated Depression Is Not Major Depressive Disorder; a Pilot Study in a Population-based Sample of the Elderly by A.D.F. Dhondt; C. Hooijer; J.H. Smit; W. van Tilburg is a Medicine article available to read on EtoBox.

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In this pilot study we investigate whether the heterogeneous variety of drugs classified in our previous work as depressogenic contributes to the occurrence of depression and whether there are differences in this contribution between major depressive disorder (MDD) and non-MDD. The study was performed in a small sample ( N = 96) of community-dwelling elderly, population-based and weighed for the distribution of age, gender and prevalence of depressive symptoms. Other aetiological aspects of depression, such as age, female gender. cerebral deterioration, a previous history of mental disorder or a family history of mental disorder, were controlled for. When subjects with a M D D were separated from the other depressed subjects, all associations with medication became stronger in MDD, except for the use of the depressogenic medication, which was less frequent in MDD. This contrast only reached the level of significance after correcting for the other aetiological contributions. In MDD, the use of depressogenic medication may play an aetiological role but other factors seem more relevant. We found a significant association between depressogenic medication and non-MDD; this strengthens o

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Author

A.D.F. Dhondt; C. Hooijer; J.H. Smit; W. van Tilburg

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 0885-6230)

Published

1996

Language

EN

Field

Medicine (Health Sciences)