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What is Novel Algorithm for Chromosome Pairing about?

This document presents a new algorithm for automatically pairing chromosomes from bone marrow cell images for leukemia diagnosis. The algorithm uses mutual information and geometric normalization to extract discriminative features from low quality chromosome images. It then formulates chromosome pairing as an optimization problem to minimize distances between homologous chromosomes and maximize distances between non-homologous ones. The algorithm was tested on a new bone marrow chromosome dataset containing

Author

Pushpa Mohan Raj

Language

EN