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The document discusses the essential role of Drosophila RIM-binding protein (DRBP) in neurotransmitter release at presynaptic active zones. It highlights that DRBP is crucial for the integrity of the active zone scaffold and for the clustering of calcium channels, which are necessary for effective synaptic transmission. The study indicates that mutations in the drbp gene lead to impaired synaptic function and reduced neurotransmitter release probability.

Author

aver030

Language

EN