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The JAVELIN Ovarian 100 trial evaluated the efficacy of avelumab combined with chemotherapy followed by avelumab maintenance versus chemotherapy alone in patients with untreated epithelial ovarian cancer. The trial was terminated early due to futility, as it did not meet its primary endpoints for improving progression-free survival. Results indicated no new safety concerns, but the addition of avelumab did not enhance outcomes, suggesting a need for alternative treatment strategies in advanced cases.
- Author
- yshparyk
- Language
- EN