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The study investigated the effect of two doses of pregabalin (150 mg and 300 mg) on the minimum alveolar concentration (MAC) of sevoflurane. It found that 300 mg pregabalin reduced the MAC of sevoflurane by 33%, while 150 mg pregabalin did not significantly reduce the MAC. Pregabalin use also led to a small reduction in postoperative pain but increased side effects in a dose-dependent manner.

Author
Nur Amaliah idrus
Language
EN

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