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Can I read Antibiotic Prophylaxis in Cranial Base Surgery on EtoBox?
Antibiotic Prophylaxis in Cranial Base Surgery by Ricardo L. Carrau; Carl Snyderman; Ivo P. Janecka; Laligam Sekhar; Chandra Sen; Frank D'Amico is a Medicine article available to read on EtoBox.
What is Antibiotic Prophylaxis in Cranial Base Surgery about?
## Abstract The role of perioperative antibiotic prophylaxis was investigated in 95 patients undergoing 100 clean‐contaminated cranial base surgeries. A variety of antibiotic regimens were employed. Potential risk factors for local infection were analyzed. Seven patients (7%) developed infections at the surgical site (meningitis, intracranial abscess, cellulitis/abscess, and osteomyelitis). Antibiotic prophylaxis for 24 hours or less was associated with a significantly increased risk of infection (__p__ 48 hours) was not more efficacious than prophylaxis for 48 hours. The surgical approach, type of reconstruction, duration of surgery, and use of drains were not significantly correlated with wound infection. The risk of intracranial infection following cranial base surgery is low despite the presence of bacterial contamination intraoperatively. Broad‐spectrum coverage of gram‐positive and gram‐negative organisms for at least 48 hours is recommended. Attention to surgical technique is important in preventing infectious complications.
Who reads Antibiotic Prophylaxis in Cranial Base Surgery?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Ricardo L. Carrau; Carl Snyderman; Ivo P. Janecka; Laligam Sekhar; Chandra Sen; Frank D'Amico
- Publisher
- Wiley
- Published
- 1991
- Language
- EN
- Field
- Medicine (Health Sciences)