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Thionucleoside disulfide cross-linked duplex DNA by Robert S. Coleman; Jason L. McCary; Ronelito J. Perez is a Chemistry article available to read on EtoBox.

What is Thionucleoside disulfide cross-linked duplex DNA about?

A strategy for covalent cross-linking of duplex oligonucleotides is described, and is based on a direct base-to-base disulfide bond formed by iodine oxidation of two appropriately positioned thionucleoside bases. Cross-link formation between 4-thio-2'-deoxyuridine and 6-thio-2'-deoxyinosine is demonstrated in three sequence contexts (3' to 3', 5' to 5', or opposed).

Who reads Thionucleoside disulfide cross-linked duplex DNA?

Author

Robert S. Coleman; Jason L. McCary; Ronelito J. Perez

Publisher

Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0040-4039)

Published

1999

Language

EN

Field

Chemistry (Physical Sciences)