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Can I read Unexpected Reaction of 2-Amino-1,4-naphthoquinone with Aldehydes: New Synthesis of Naphtho[2,1-d]oxazole Compounds on EtoBox?
Unexpected Reaction of 2-Amino-1,4-naphthoquinone with Aldehydes: New Synthesis of Naphtho[2,1-d]oxazole Compounds by Sam Van Aeken; Jurgen Deblander; Johan De Houwer; Timothy Mosselmans; Kourosch Abbaspour Tehrani is a Chemistry article available to read on EtoBox.
What is Unexpected Reaction of 2-Amino-1,4-naphthoquinone with Aldehydes: New Synthesis of Naphtho[2,1-d]oxazole Compounds about?
Treatment of 3-substituted 2-amino-1,4-naphthoquinones 3 with an aldehyde in a solution of hydrobromic acid in acetic acid led to 2,4-disubstituted naphtho[2,1-d]oxazol-5-ols. The outcome of this simple conversion is even more remarkable in view of the very similar reactions reported in literature, which all give rise to completely different products. Furthermore, the acquired naphthoxazoles 5e11 could be oxidatively ring opened by means of PIFA or CAN into a series of N-acylated 2-amino-1,4-naphthoquinones. A synthetic pathway towards 2-substituted naphtho [2,3-d]oxazole-4,9-diones was also disclosed as the outcome of CAN mediated oxidation of a 4-chloronaphtho[2,1-d]oxazol-5-ol.
Who reads Unexpected Reaction of 2-Amino-1,4-naphthoquinone with Aldehydes: New Synthesis of Naphtho[2,1-d]oxazole Compounds?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Sam Van Aeken; Jurgen Deblander; Johan De Houwer; Timothy Mosselmans; Kourosch Abbaspour Tehrani
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0040-4020)
- Published
- 2011
- Language
- EN
- Field
- Chemistry (Physical Sciences)