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ROS and DNA Damage in Aging Monocytes by Ends 10 is a document available to read on EtoBox.
This study investigates the effects of aging and hypercholesterolemia on oxidative stress, DNA damage, and apoptosis in monocytes from apolipoprotein E-deficient mice. Results show that atherosclerotic mice exhibit increased monocytosis, pro-inflammatory cytokines, and reactive oxygen species (ROS), leading to significant DNA fragmentation and apoptosis in monocytes. The findings suggest that systemic inflammation and oxidative stress are critical factors in the progression of atherosclerosis, highlighting
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- Ends 10
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- EN