Can I read Antibiotic resistance spectrum of E. coli strains from different samples and age-grouped patients: a 10-year retrospective study on EtoBox?

Antibiotic resistance spectrum of E. coli strains from different samples and age-grouped patients: a 10-year retrospective study by Sipei Wang; Sheng Zhao; Yangxiao Zhou; Shanshan Jin; Tinghua Ye; Xinling Pan is a Medicine article available to read on EtoBox.

What is Antibiotic resistance spectrum of E. coli strains from different samples and age-grouped patients: a 10-year retrospective study about?

## Objective __Escherichia coli__ (__E. coli__) is the most common opportunistic clinical micro-organism with high drug resistance. This study aimed to analyse the resistance pattern of __E. coli__ according to patient age and clinical sample type. ## Design and setting This retrospective observational study was conducted in a tertiary hospital in southeastern China. ## Participants __E. coli__ strains were isolated from blood, urine and sputum of infected inpatients. The patients were divided into four age groups: children (0–14 years old, including neonatal and non-neonatal groups), youths (15–40 years old), middle-aged (41–60 years old) and old (>60 years old). ## Results A total of 7165 __E. coli__ strains were collected from all samples. Compared with urine and blood isolates, more sputum isolates were resistant against 12 tested antibiotics. Furthermore, urine isolates were more resistant to levofloxacin than sputum and blood isolates. Although the patients’ age was not associated with resistance rates of __E. coli__ strains isolated from blood, a larger proportion of urine-derived strains from youths were resistant to sulfamethoxazole-trimethoprim and piperacillin-tazobactam

Who reads Antibiotic resistance spectrum of E. coli strains from different samples and age-grouped patients: a 10-year retrospective study?

Author

Sipei Wang; Sheng Zhao; Yangxiao Zhou; Shanshan Jin; Tinghua Ye; Xinling Pan

Publisher

BMJ Publishing Group

Published

2023

Language

EN

Field

Medicine (Health Sciences)