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Boli Mieloproliferative Cronice: LMC și Tratament by Ema Țurcaș is a document available to read on EtoBox.

What is Boli Mieloproliferative Cronice: LMC și Tratament about?

The document discusses chronic myeloproliferative diseases (CMDs), including chronic myeloid leukemia (CML). CML is characterized by the excessive proliferation of the granulocytic lineage. It has two phases - a chronic phase lasting 3-5 years on average, and a terminal blast crisis phase similar to acute leukemia. The pathogenic mechanism involves a translocation between chromosomes 9 and 22, known as the Philadelphia chromosome, which produces the BCR-ABL fusion gene. Treatment of the chronic phase involv

Author
Ema Țurcaș
Language
EN