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Can I read Vaccination with Aedes aegypti AgBR1 Delays Lethal Mosquito-Borne Zika Virus Infection in Mice on EtoBox?
Vaccination with Aedes aegypti AgBR1 Delays Lethal Mosquito-Borne Zika Virus Infection in Mice by Wang, Yuchen; Marin-Lopez, Alejandro; Jiang, Junjun; Ledizet, Michel; Fikrig, Erol is a Medicine article available to read on EtoBox.
What is Vaccination with Aedes aegypti AgBR1 Delays Lethal Mosquito-Borne Zika Virus Infection in Mice about?
Zika Virus (ZIKV) is transmitted primarily by __Aedes aegypti__ mosquitoes, resulting in asymptomatic infection, or acute illness with a fever and headache, or neurological complications, such as Guillain-Barre syndrome or fetal microcephaly. Previously, we determined that AgBR1, a mosquito salivary protein, induces inflammatory responses at the bite site, and that passive immunization with AgBR1 antiserum influences mosquito-transmitted ZIKV infection. Here, we show that the active immunization of mice with AgBR1 adjuvanted with aluminum hydroxide delays lethal mosquito-borne ZIKV infection, suggesting that AgBR1 may be used as part of a vaccine to combat ZIKV.
Who reads Vaccination with Aedes aegypti AgBR1 Delays Lethal Mosquito-Borne Zika Virus Infection in Mice?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Wang, Yuchen; Marin-Lopez, Alejandro; Jiang, Junjun; Ledizet, Michel; Fikrig, Erol
- Publisher
- MDPI AG; Multidisciplinary Digital Publishing Institute (MDPI); Basel: MDPI AG, 2013- (ISSN 2076-393X)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)