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Can I read Synthesis of a Novel 6,14-Epoxymorphinan Derivative and Its Pharmacology on EtoBox?
Synthesis of a Novel 6,14-Epoxymorphinan Derivative and Its Pharmacology by Toru Nemoto; Hideaki Fujii; Minoru Narita; Kan Miyoshi; Atsushi Nakamura; Tsutomu Suzuki; Hiroshi Nagase is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Synthesis of a Novel 6,14-Epoxymorphinan Derivative and Its Pharmacology about?
A novel 6,14-epoxymorphinan benzamide derivative (NS22) was synthesized, which showed opioid j receptor agonistic activity in the [ 35 S]GTPcS binding assay. The antinociceptive effect of NS22 was evaluated in the tail-flick and the hot-plate test. This compound showed a potent antinociceptive activity in mice by sc administration, which was attenuated with nor-BNI (selective opioid j receptor antagonist).
Who reads Synthesis of a Novel 6,14-Epoxymorphinan Derivative and Its Pharmacology?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Toru Nemoto; Hideaki Fujii; Minoru Narita; Kan Miyoshi; Atsushi Nakamura; Tsutomu Suzuki; Hiroshi Nagase
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0960-894X)
- Published
- 2008
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)