Opening book details…
Can I read Potential of Magnetic Resonance Spectroscopy to Detect Metastasis in Axillary Lymph Nodes in Breast Cancer on EtoBox?
Potential of Magnetic Resonance Spectroscopy to Detect Metastasis in Axillary Lymph Nodes in Breast Cancer by Vuthaluru Seenu; Maganti N. Pavan Kumar; Uma Sharma; Siddhartha Datta Gupta; Sadanand N. Mehta; Naranamangalam R. Jagannathan is a Medicine article available to read on EtoBox.
What is Potential of Magnetic Resonance Spectroscopy to Detect Metastasis in Axillary Lymph Nodes in Breast Cancer about?
Focused pathological evaluation of axillary lymph nodes in breast cancer is gaining importance. Nuclear magnetic resonance (NMR) spectroscopy that assesses the whole of the specimen has the potential in evaluating micrometastases. The biochemical changes associated with breast cancer metastases in axillary nodes by in vitro NMR and its use in the detection of axillary metastases in a clinical setting in comparison with conventional histopathology is presented in this study. Eighty-eight lymph nodes obtained from 30 patients with breast cancer were investigated. Histopathology revealed metastases in 20 nodes from 11 patients, while in vitro NMR spectroscopy revealed metastases in 22 nodes. Out of these 22 nodes, 16 were the same, which showed metastases on histopathology, while 6 nodes have shown metastases only on in vitro magnetic resonance spectroscopy (MRS). These 6 nodes with suspicion of metastases on MRS were subjected to reevaluation with serial sectioning and immunohistochemistry, but no additional metastases were revealed. Forty metabolites could be identified from the MR spectrum of lymph nodes. The levels of the glycerophosphocholine-phosphocholine (GPC-PC), choline, lac
Who reads Potential of Magnetic Resonance Spectroscopy to Detect Metastasis in Axillary Lymph Nodes in Breast Cancer?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Vuthaluru Seenu; Maganti N. Pavan Kumar; Uma Sharma; Siddhartha Datta Gupta; Sadanand N. Mehta; Naranamangalam R. Jagannathan
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0730-725X)
- Published
- 2005
- Language
- EN
- Field
- Medicine (Health Sciences)