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Chronic calorie restriction (CR) has been shown to reduce the severity of experimental autoimmune encephalomyelitis (EAE), a model for multiple sclerosis (MS), in mice without suppressing immune function. The study found that CR led to less inflammation, demyelination, and axon injury, while a high-calorie diet did not affect EAE progression. These findings suggest that CR could be a potential therapeutic strategy for MS, warranting further exploration in clinical settings.

Author

lgtrainer

Language

EN