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This study investigates the role of epithelialized tunnels in hidradenitis suppurativa (HS) as active contributors to inflammation rather than mere end-stage features. Biopsy specimens from patients with HS show that these tunnels exhibit immunological activity, including increased inflammatory cytokines and immune cell infiltration, particularly T cells and neutrophils. Treatment with the IL-17RA antagonist brodalumab resulted in reduced tunnel size and drainage, highlighting their significance in HS patho

Author

tengkumlufthi

Language

EN