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Can I read P088 Study of EC cells in patients with pernicious anemia on EtoBox?
P088 Study of EC cells in patients with pernicious anemia by L. Macukanovic-Golubovic; M. Milenovic; G. Marjanovic; M. Vucic; E. Simonovic; M. Mladenovic; G. Rancic is a Medicine article available to read on EtoBox.
What is P088 Study of EC cells in patients with pernicious anemia about?
Patient and Methods: This was a prospective randomized, single-center, open-label, 12-week case-control study of epoetin alfa in pediatric patients with acute lymphoblastic leukemia (ALL) in remission receiving maintenance chemotherapy. Sixty patients were randomly assigned to receive either epoetin alfa (rHuEPO group = 30 cases, 17 males & 13 female), or no epoetin alfa (control group = 30 cases, 16 males & 14 females). Both groups were matched as regard age, sex, baseline Hb concentration, remission state, chemotherapy regimen, numbers and amount of blood transfusion, and leukemia state (both were low and standard risk). The median age was 7 years (range 3 11 y). Epoetin alfa was administered at a dose of 450 IU/kg, once weekly, subcutaneously (sc) for 12 consecutive weeks. Endpoints were changes in hematologic and quality of life (QOL) parameters. Results: Among the 30 patients evaluable for hematologic response, the mean increase in Hb from baseline to time of final evaluation was 2.0±1.2 g/dl (p < 0.05). An increase in Hb of 2 g/dl, in the absence of blood transfusion, occurred in 70% of patients (21 of 30 patients) who were on the study for 30 days. The overall response rate
Who reads P088 Study of EC cells in patients with pernicious anemia?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- L. Macukanovic-Golubovic; M. Milenovic; G. Marjanovic; M. Vucic; E. Simonovic; M. Mladenovic; G. Rancic
- Publisher
- Elsevier Science; Elsevier ; Churchill Livingstone; Elsevier BV (ISSN 0268-960X)
- Published
- 2007
- Language
- EN
- Field
- Medicine (Health Sciences)