Can I read Vinblastine in the treatment of advanced Hodgkin's disease on EtoBox?

Vinblastine in the treatment of advanced Hodgkin's disease by Dr. W. Davies Sohier Jr.; Rose K. L. Wong; Alan C. Aisenberg is a Medicine article available to read on EtoBox.

What is Vinblastine in the treatment of advanced Hodgkin's disease about?

In 35 cases of advanced Hodgkin's disease (stage IIIB to IVB), of whom 33 were no longer responsive to the alkylating agents, vinblastine produced clinically useful remissions in 22 patients or 64%. Complete objective responses were unusual but one third of these cases experienced partial remissions of more than 1 year's duration accompanied by marked amelioration of symptoms. Serious toxicity was not encountered. There was no relationship between vinblastine response and prior responses to the alkylating agents. Despite the disadvantage of being secondary therapy, vinblastine appeared superior to the alkylating agents in the quality and length of remissions it produced. ## INCE THE DISCOVEKY OF THE PERIWINKLE S alkaloid vinblastine (vincaleukoblastine) in the late 1950's and its description as a cancer chemotherapeutic conipound,g, 13 a number of reports have appeared concerning its efficacy in neoplastic disease in general-O , 3, 5 , 6, l 4 1 I7 and in Hoclgkin's disease in particular.J, 11, 1H Although vinblastine has proven to be a t least as effective as the alkylating agents, few reports in the American literature have iridicated the value of vinblastine or the clinical setti

Who reads Vinblastine in the treatment of advanced Hodgkin's disease?

Author

Dr. W. Davies Sohier Jr.; Rose K. L. Wong; Alan C. Aisenberg

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0008-543X)

Published

1968

Language

EN

Field

Medicine (Health Sciences)