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Induction Chemotherapy in Advanced Head and Neck Cancer by docarunradhakrishnan is a document available to read on EtoBox.

What is Induction Chemotherapy in Advanced Head and Neck Cancer about?

This phase III trial evaluated the efficacy of induction chemotherapy (IC) followed by chemoradiotherapy (CRT) in patients with N2 or N3 locally advanced head and neck cancer. The study found no significant improvement in overall survival (OS) or other secondary endpoints when comparing IC + CRT to CRT alone, although serious adverse events were more common in the IC group. The trial was underpowered due to lower-than-expected patient accrual, leading to the conclusion that routine use of IC in this patient

Author

docarunradhakrishnan

Language

EN