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Can I read Hospital Volume–outcome Relationship in Total Knee Arthroplasty: a Systematic Review and Dose–response Meta-analysis on EtoBox?
Hospital Volume–outcome Relationship in Total Knee Arthroplasty: a Systematic Review and Dose–response Meta-analysis by C. M. Kugler; K. Goossen; T. Rombey; K. K. De Santis; T. Mathes; J. Breuing; S. Hess; R. Burchard; D. Pieper is a Medicine article available to read on EtoBox.
What is Hospital Volume–outcome Relationship in Total Knee Arthroplasty: a Systematic Review and Dose–response Meta-analysis about?
## Abstract ## Purpose This systematic review and dose–response meta-analysis aimed to investigate the relationship between hospital volume and outcomes for total knee arthroplasty (TKA). ## Methods MEDLINE, Embase, CENTRAL and CINAHL were searched up to February 2020 for randomised controlled trials and cohort studies that reported TKA performed in hospitals with at least two different volumes and any associated patient-relevant outcomes. The adjusted effect estimates (odds ratios, OR) were pooled using a random-effects, linear dose–response meta-analysis. Heterogeneity was quantified using the I^2^-statistic. ROBINS-I and the GRADE approach were used to assess the risk of bias and the confidence in the cumulative evidence, respectively. ## Results A total of 68 cohort studies with data from 1985 to 2018 were included. The risk of bias for all outcomes ranged from moderate to critical. Higher hospital volume may be associated with a lower rate of early revision ≤ 12 months (narrative synthesis of k = 7 studies, n = 301,378 patients) and is likely associated with lower mortality ≤ 3 months (OR = 0.91 per additional 50 TKAs/year, 95% confidence interval [0.87–0.95], k = 9, n = 2,638
Who reads Hospital Volume–outcome Relationship in Total Knee Arthroplasty: a Systematic Review and Dose–response Meta-analysis?
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- Author
- C. M. Kugler; K. Goossen; T. Rombey; K. K. De Santis; T. Mathes; J. Breuing; S. Hess; R. Burchard; D. Pieper
- Publisher
- Springer Science and Business Media LLC
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)