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2270: Combined Fast Neutron Irradiation and Permanent Prostate Brachytherapy in Intermediate and Poor Risk Prostate Cancer: Expanded Results of Phase II Trial by R. Patel; J.D. Forman; M. Cher; D. Perry; S. Bolton; C. Zuniga; M. Joiner is a Medicine article available to read on EtoBox.

What is 2270: Combined Fast Neutron Irradiation and Permanent Prostate Brachytherapy in Intermediate and Poor Risk Prostate Cancer: Expanded Results of Phase II Trial about?

zone of the treated prostate on T2-weighted images was relatively thin and only slightly higher in signal intensity than the central gland. On T1-weighted imaging, the treated prostate is of uniform signal intensity with no differentiation between the zones. One patient with biochemical recurrence had a vague mass like area of low signal intensity suspicious for tumor. The MRI results of the remaining men were interpreted as normal. Fifteen MRSI data sets were collected but ten were found to be uninterpretable including the patient with an abnormal MRI and biochemical failure. No abnormal spectra suspicious for tumor activity are appreciated in the 5 men with interpretable MRSI. Conclusions: MRI and MRSI with endorectal coil following LDRPB alone is feasible in our hands but a readable MRSI was achieved in a minority of patients on this study. MRI, specifically axial T2 weighted imaging of the treated prostate, was not useful. Outside of a study, we do not recommend MRI and MRSI to evaluate for local recurrence.

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Author

R. Patel; J.D. Forman; M. Cher; D. Perry; S. Bolton; C. Zuniga; M. Joiner

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)

Published

2006

Language

EN

Field

Medicine (Health Sciences)