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Baclofen: Mechanism and Effects Explained by Bluebaby Agaznog is a document available to read on EtoBox.
Baclofen is an agonist at presynaptic GABA-B receptors in the spinal cord where it inhibits the transmission of monosynaptic and polysynaptic reflexes, likely by preventing the release of excitatory neurotransmitters. It has general central nervous system depressant effects and may provide analgesia by decreasing nociceptive neuron responsiveness at both spinal and supraspinal sites.
- Author
- Bluebaby Agaznog
- Language
- EN