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Frontotemporal Dementia with Parkinsonism Presenting as Posterior Cortical Atrophy by Francesca Spagnolo; Daniela Ceppi; Rosalinda Cardamone; Monica Falautano; Vittorio Martinelli; Giancarlo Comi; Daniela Perani; Maria A. Volonté is a Medicine article available to read on EtoBox.

What is Frontotemporal Dementia with Parkinsonism Presenting as Posterior Cortical Atrophy about?

Posterior cortical atrophy (PCA) represents a degenerative disorder characterized by the development of higherorder visual deficit. 1 PCA may result from heterogeneous pathologies that make up tauopathies. An increasing number of mutations in the tau gene (microtubule-associated protein tau [MAPT]) causes a wide spectrum of clinical presentations known as frontotemporal dementia with parkinsonism linked to chromosome-17 (FTDP-17). 2 Symptomatology usually involves executive dysfunction and altered personality and behavior, with patients displaying parkinsonian features. We describe the case of a woman with PCA who further developed asymmetric motor signs. A mutation in the MAPT gene was detected, and a diagnosis of FTDP-17 was formulated. To our knowledge, this is the very first report of a patient suffering from FTDP-17 diagnosed with posterior cortical atrophy. ## Case Report A 55-year-old woman started suffering in 2006 from altered perception of human faces. Initially the visual distortion was fluctuating; over the following year it became constant, and she could not recognize her husband and children by their faces anymore. She further developed visuospatial deficits, with dif

Who reads Frontotemporal Dementia with Parkinsonism Presenting as Posterior Cortical Atrophy?

Author

Francesca Spagnolo; Daniela Ceppi; Rosalinda Cardamone; Monica Falautano; Vittorio Martinelli; Giancarlo Comi; Daniela Perani; Maria A. Volonté

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0885-3185)

Published

2011

Language

EN

Field

Medicine (Health Sciences)