Can I read Comparison of Modified Supports on the Base of Glycoprotein Interaction Studies and of Adsorption Investigations on EtoBox?

Comparison of Modified Supports on the Base of Glycoprotein Interaction Studies and of Adsorption Investigations by Henning Rosenfeld; Jolita Aniulyte; Heike Helmholz; Jolanta Liesiene; Peter Thiesen; Bernd Niemeyer; Andreas Prange is a Chemistry article available to read on EtoBox.

What is Comparison of Modified Supports on the Base of Glycoprotein Interaction Studies and of Adsorption Investigations about?

The features of matrices, suitable for affinity chromatography, have been extensively investigated and got subject for several reviews. But these investigations show, that there is still a lack in adsorbent characterization and a demand of comparative investigations of adsorbents, based on different materials with a range of different surface functionalities. In this work the performance of self-prepared silica and cellulose-based adsorbents were compared with commercially available polymeric supports. A model system was chosen comprising the lectins concanavalin A (ConA) and wheat germ agglutinin (WGA), which were covalently attached to the support matrices, combining the selectivity of the lectin-sugar interaction with the chemical and mechanical properties of the support that influence the efficacy of the prepared adsorbent. The verification of the different supports provides information about tayloring carbohydrate specific lectin adsorbents. The characterization outlines the main features of the different adsorbents and takes into account the properties of the pure supports. It encompasses immobilization kinetics and isotherms as well as the description of the binding capacity

Who reads Comparison of Modified Supports on the Base of Glycoprotein Interaction Studies and of Adsorption Investigations?

Author

Henning Rosenfeld; Jolita Aniulyte; Heike Helmholz; Jolanta Liesiene; Peter Thiesen; Bernd Niemeyer; Andreas Prange

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 1873-3778)

Published

2005

Language

EN

Field

Chemistry (Physical Sciences)