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What is Nicotine and Cotinine Detection in Urine and Saliva about?

A rapid and sensitive method for determining nicotine, cotinine, and related alkaloids in human urine and saliva was developed using automated in-tube solid-phase microextraction coupled with liquid chromatography–mass spectrometry (LC–MS). The method achieved separation of compounds within 7 minutes and demonstrated significantly higher sensitivity compared to direct injection methods. Successful application of this method allows for accurate analysis of nicotine intake and smoking status without interfere

Author

nisof37911

Language

EN