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The impact of Highly Active Antiretroviral Therapy (HAART) on the clinical features of HIV - related oral lesions in Nigeria by Olaniyi O Taiwo; Zuwaira Hassan is a Medicine article available to read on EtoBox.

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## Background: This study aimed to determine the therapeutic effects of highly active anti-retroviral therapy (haart) on the clinical presentations of hiv related oral lesions (hiv-rols) in an adult nigerian population. ## Methods: A 5 month prospective study on haart naïve hiv positive adults recruited into the haart program of an aids referral centre. hiv-rols were diagnosed clinically by the eec clearinghouse on oral problems related to hiv infection. baseline clinical features of hiv-rols was documented by clinical photographs using sony(r) 5.2 m cybershot digital camera. post haart monthly review was conducted using clinical photographs. ## Results: A total of 142 patients were seen. age range was 19 - 75 years. mean age was 35.6 +/- 10.5 (sd). eighty (56.3%) were females. prevalence of hiv-rols was 43.7%. oral candidiasis (22.4%) was the most prevalent hiv-rol. 114 (83.2%) patients had clinical aids at presentation (cdc 1993). 89.4% were placed on tenofovir/emtricitabine +;nevirapine, 9.9% on tenofovir/emtricitabine + efavirenz. there was strong decline in the clinical features of oral candidiasis from a month of commencing haart. oral hairy leukoplakia was slow in responding

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Author

Olaniyi O Taiwo; Zuwaira Hassan

Publisher

BioMed Central; Springer (Biomed Central Ltd.); [London]: BioMed Central, 2004-; Springer Science and Business Media LLC (ISSN 1742-6405)

Published

2010

Language

EN

Field

Medicine (Health Sciences)