Opening book details…
Can I read Saccharomyces cerevisiae S288C genome annotation: a working hypothesis on EtoBox?
Saccharomyces cerevisiae S288C genome annotation: a working hypothesis by Dianna G. Fisk; Catherine A. Ball; Kara Dolinski; Stacia R. Engel; Eurie L. Hong; Laurie Issel-Tarver; Katja Schwartz; Anand Sethuraman; David Botstein; J. Michael Cherry is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Saccharomyces cerevisiae S288C genome annotation: a working hypothesis about?
## Abstract The __S. cerevisiae__ genome is the most well‐characterized eukaryotic genome and one of the simplest in terms of identifying open reading frames (ORFs), yet its primary annotation has been updated continually in the decade since its initial release in 1996 (Goffeau __et al.__, 1996). The __Saccharomyces__ Genome Database (SGD; www.yeastgenome.org) (Hirschman __et al.__, 2006), the community‐designated repository for this reference genome, strives to ensure that the __S. cerevisiae__ annotation is as accurate and useful as possible. At SGD, the __S. cerevisiae__ genome sequence and annotation are treated as a working hypothesis, which must be repeatedly tested and refined. In this paper, in celebration of the tenth anniversary of the completion of the __S. cerevisiae__ genome sequence, we discuss the ways in which the __S. cerevisiae__ sequence and annotation have changed, consider the multiple sources of experimental and comparative data on which these changes are based, and describe our methods for evaluating, incorporating and documenting these new data. Copyright © 2006 John Wiley & Sons, Ltd.
Who reads Saccharomyces cerevisiae S288C genome annotation: a working hypothesis?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Dianna G. Fisk; Catherine A. Ball; Kara Dolinski; Stacia R. Engel; Eurie L. Hong; Laurie Issel-Tarver; Katja Schwartz; Anand Sethuraman; David Botstein; J. Michael Cherry
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); John Wiley & Sons Inc.; [Chichester]; [New York]: John Wiley & Sons, ©1985-; Wiley; Hindawi Limited (ISSN 0749-503X)
- Published
- 2006
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)