Can I read Agrarian diet and diseases of affluence – Do evolutionary novel dietary lectins cause leptin resistance? on EtoBox?

Agrarian diet and diseases of affluence – Do evolutionary novel dietary lectins cause leptin resistance? by Tommy Jönsson; Stefan Olsson; Bo Ahrén; Thorkild C Bøg-Hansen; Anita Dole; Staffan Lindeberg is a Medicine article available to read on EtoBox.

What is Agrarian diet and diseases of affluence – Do evolutionary novel dietary lectins cause leptin resistance? about?

## Background The global pattern of varying prevalence of diseases of affluence, such as obesity, cardiovascular disease and diabetes, suggests that some environmental factor specific to agrarian societies could initiate these diseases. ## Presentation of the hypothesis We propose that a cereal-based diet could be such an environmental factor. Through previous studies in archaeology and molecular evolution we conclude that humans and the human leptin system are not specifically adapted to a cereal-based diet, and that leptin resistance associated with diseases of affluence could be a sign of insufficient adaptation to such a diet. We further propose lectins as a cereal constituent with sufficient properties to cause leptin resistance, either through effects on metabolism central to the proper functions of the leptin system, and/or directly through binding to human leptin or human leptin receptor, thereby affecting the function. ## Testing the hypothesis Dietary interventions should compare effects of agrarian and non-agrarian diets on incidence of diseases of affluence, related risk factors and leptin resistance. A non-significant (p = 0.10) increase of cardiovascular mortality was

Who reads Agrarian diet and diseases of affluence – Do evolutionary novel dietary lectins cause leptin resistance??

Author

Tommy Jönsson; Stefan Olsson; Bo Ahrén; Thorkild C Bøg-Hansen; Anita Dole; Staffan Lindeberg

Publisher

BioMed Central; Springer (Biomed Central Ltd.); London: BioMed Central, 2001-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1472-6823)

Published

2005

Language

EN

ISBN

9781472682352

Field

Medicine (Health Sciences)