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S ## Immunosuppressants Cutaneous, subcutaneous and pulmonary phaeohyphomycosis due to Alternaria species: case report A 66-year-old man developed cutaneous, subcutaneous and pulmonary phaeohyphomycosis due to Alternaria species following treatment with methylprednisolone, mycophenolate mofetil, prednisolone and tacrolimus [routes not stated; not all dosages stated]. The man presented with a 3 month history of two enlarging lesions on the left middle finger. Five months previously, he had undergone a cardiac transplant due to ischaemic cardiomyopathy, and received treatment with methylprednisolone for transplant rejection post-operatively. His immunosuppressive regimen consisted of prednisolone 15mg daily, mycophenolate mofetil 250mg twice daily and tacrolimus 5mg twice daily. On examination, he was found to have tender erythematous nodules over the distal interphalangeal joint and middle phalynx, measuring 2 × 2 cm and 1.5 × 1.5 cm, respectively. Subsequent shave biopsy revealed hyperparakeratosis with an acute inflammatory infiltrate overlying pseudoepiheliomatous hyperplasia and spongiotic epidermis. Active chronic inflammatory infiltrate with focal micro-abscesses were observed

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Publisher

Adis International Limited (now part of Wolters Kluwer Health); Springer-Verlag; Springer Science and Business Media LLC (ISSN 0114-9954)

Published

2018

Language

EN

Field

Medicine (Health Sciences)