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What is Caloric Restriction about?
This study investigated the effects of litter size reduction and post-weaning caloric restriction on rat liver glucose metabolism and whole-body glucose homeostasis. The results showed that litter size reduction did not affect liver glucose metabolism or glucose tolerance at 60 days of age. However, caloric restriction increased basal liver glucose release, decreased gluconeogenesis, and slowed glycemic decay during an insulin tolerance test, which could compromise glucose homeostasis and prompt insulin res
- Author
- Sabrina Jones
- Language
- EN