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Genetic variation for the positioning of wing veins in Drosophila melanogaster by Kelli Birdsall; Erika Zimmerman; Katherine Teeter; Greg Gibson is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Genetic variation for the positioning of wing veins in Drosophila melanogaster about?

To define the components of variation for wing shape in Drosophila in relation to what is known about the developmental control of wing patterning, we have characterized shape variation in the wings of 12 randomly chosen highly inbred lines. Despite large differences in wing size between males and females, and between flies reared at 18 degrees C or 25 degrees C, wing shape is remarkably unaffected by these variables and is highly line specific. The shape of each intervein region of the wing appears to be independently regulated at the genetic level, consistent with the role of secreted growth factors in establishing the locations of wing veins. Sex and temperature were found to have different effects on cell number in two intervein regions, with the result that wing shape is to a large extent independent of cell density. Dietary cholesterol was also shown to affect the breadth of the central intervein region, consistent with an effect on the strength of Hedgehog signaling during wing development. We conclude that wing shape is under tighter genetic control than wing size, and hypothesize that this control is achieved in large part by gene activity at the level of wing vein determi

Who reads Genetic variation for the positioning of wing veins in Drosophila melanogaster?

Author

Kelli Birdsall; Erika Zimmerman; Katherine Teeter; Greg Gibson

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 1520-541X)

Published

2001

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)