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Can I read Genomic Sequencing of Pleistocene Cave Bears on EtoBox?
Genomic Sequencing of Pleistocene Cave Bears by James P. Noonan; Michael Hofreiter; Doug Smith; James R. Priest; Nadin Rohland; Gernot Rabeder; Johannes Krause; J. Chris Detter; Svante Pääbo; Edward M. Rubin is a nonfiction available to read on EtoBox.
What is Genomic Sequencing of Pleistocene Cave Bears about?
Despite the greater information content of genomic DNA, ancient DNA studies have largely been limited to the amplification of mitochondrial sequences. Here we describe metagenomic libraries constructed with unamplified DNA extracted from skeletal remains of two 40,000-year-old extinct cave bears. Analysis of ∼1 megabase of sequence from each library showed that despite significant microbial contamination, 5.8 and 1.1% of clones contained cave bear inserts, yielding 26,861 base pairs of cave bear genome sequence. Comparison of cave bear and modern bear sequences revealed the evolutionary relationship of these lineages. The metagenomic approach used here establishes the feasibility of ancient DNA genome sequencing programs.
Who reads Genomic Sequencing of Pleistocene Cave Bears?
It is typically read by self-directed learners exploring a subject in depth.
Common subject areas: history, science, philosophy, social sciences.
- Author
- James P. Noonan; Michael Hofreiter; Doug Smith; James R. Priest; Nadin Rohland; Gernot Rabeder; Johannes Krause; J. Chris Detter; Svante Pääbo; Edward M. Rubin
- Publisher
- American Association for the Advancement of Science (AAAS)
- Published
- 2005
- Language
- EN
- Category
- nonfiction
- Subjects
- Science, Stem
More by James P. Noonan; Michael Hofreiter; Doug Smith; James R. Priest; Nadin Rohland; Gernot Rabeder; Johannes Krause; J. Chris Detter; Svante Pääbo; Edward M. Rubin
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