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Application of Umbilical Cord Serum Eyedrops for the Treatment of Dry Eye Syndrome by Kyung-Chul Yoon; Seong-Kyu Im; Yeoung-Geol Park; Young-Do Jung; Seong-Yeul Yang; Jin Choi is a Medicine article available to read on EtoBox.

What is Application of Umbilical Cord Serum Eyedrops for the Treatment of Dry Eye Syndrome about?

## Purpose: To investigate the efficacy of umbilical cord serum eyedrops for the treatment of severe dry eye syndrome. ## Methods: Fifty-five eyes of 31 patients with severe dry eye syndrome were treated with umbilical cord serum eyedrops. symptom scoring, tear film break-up time (but), schirmer test, corneal sensitivity test, and corneal fluorescein staining were performed before and 1 and 2 months after treatment, and conjunctival impression cytology was performed before and 2 months after treatment. the concentrations of epidermal growth factor (egf), vitamin a, and transforming growth factor-beta (tgf-beta) in umbilical cord serum and normal peripheral blood serum were measured. ## Results: Two months after treatment, significant improvement was observed in symptom score (from 3.07 +/- 0.54 to 0.96 +/- 0. 58), but (from 3.96 +/- 1.56 to 5.45 +/- 2.54 seconds), and keratoepitheliopathy score (from 4.87 +/- 3.22 to 1.71 +/- 1.84) (p < 0.01). there was no statistically significant change in schirmer and corneal sensitivity tests. in impression cytology, the grade of squamous metaplasia (from 2.35 +/- 0.72 to 1.44 +/- 0.69) and goblet cell density (from 80.91 +/- 31.53 to 154.68 +/

Who reads Application of Umbilical Cord Serum Eyedrops for the Treatment of Dry Eye Syndrome?

Author

Kyung-Chul Yoon; Seong-Kyu Im; Yeoung-Geol Park; Young-Do Jung; Seong-Yeul Yang; Jin Choi

Publisher

Ovid Technologies (Wolters Kluwer Health)

Published

2006

Language

EN

Field

Medicine (Health Sciences)