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COVID vaccination and asthma exacerbation: might there be a link? by Marta Colaneri; Maria De Filippo; Amelia Licari; Alessia Marseglia; Laura Maiocchi; Alessandra Ricciardi; Angelo Corsico; Gianluigi Marseglia; Mario Umberto Mondelli; Raffaele Bruno is a Medicine article available to read on EtoBox.

What is COVID vaccination and asthma exacerbation: might there be a link? about?

Introduction There is ongoing debate regarding the role of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in asthma exacerbation, and its long-term impact on the lung function of individuals with asthma. In contrast, the potential impact of coronavirus disease 2019 (COVID-19) vaccination on asthma is entirely unexplored. Case study This study examined a challenging case of severe asthma exacerbation in a 28-year-old female following two doses of the mRNA-based vaccine BNT162b2 (Pfizer-BioNTech) at IRCCS Policlinico San Matteo in Pavia, Italy. The patient, a fourth-year resident at the hospital, was vaccinated in early 2021. She was an occasional smoker with a 10-year history of asthma and seasonal allergic rhinitis. She tested negative for SARS-CoV-2 on several molecular swabs and serology tests. Results After receiving the second dose of vaccine, the patient started to experience worsening of respiratory symptoms. Following several episodes and a severe asthma attack, the patient required treatment with mepolizumab, a biologic drug (interleukin-5) antagonist monoclonal antibody. Conclusion This single case study is insufficient to draw conclusions about the

Who reads COVID vaccination and asthma exacerbation: might there be a link??

Author

Marta Colaneri; Maria De Filippo; Amelia Licari; Alessia Marseglia; Laura Maiocchi; Alessandra Ricciardi; Angelo Corsico; Gianluigi Marseglia; Mario Umberto Mondelli; Raffaele Bruno

Publisher

Elsevier BV

Published

2021

Language

EN

Field

Medicine (Health Sciences)