Can I read Energy restriction early in life and colon carcinoma risk : Results of the Netherlands Cohort Study after 7.3 years of follow-up on EtoBox?

Energy restriction early in life and colon carcinoma risk : Results of the Netherlands Cohort Study after 7.3 years of follow-up by Miranda J. M. Dirx; Piet A. van den Brandt; R. Alexandra Goldbohm; L. H. Lumey is a Medicine article available to read on EtoBox.

What is Energy restriction early in life and colon carcinoma risk : Results of the Netherlands Cohort Study after 7.3 years of follow-up about?

## Abstract ## BACKGROUND This study evaluated the effects of severe undernutrition during adolescence and subsequent colon carcinoma risk. ## METHODS The authors evaluated The Netherlands Cohort Study on Diet and Cancer (NLCS) among 62,573 women and 58,279 men aged 55–69 years at baseline. Information on diet and risk factors was collected by questionnaire in 1986. Additional information was collected concerning residence during the hunger winter (1944–1945), the World War II years (1940–1944), and father's employment status during the economic depression of 1932–1940, which were used as indicators of exposure. After 7.3 years of follow‐up, 807 colon carcinoma cases (388 females and 419 males) were available for analysis. ## RESULTS Multivariate analysis showed that both men and women who had lived in a western city in 1944–1945 had a decreased colon carcinoma risk (men: relative risk [RR] = 0.85, 95% confidence interval [CI] = 0.62–1.16; women: RR = 0.80, 95%CI = 0.59–1.09). No association between colon carcinoma risk and urban versus rural residence was found during the war years (1940–1944). Having an unemployed father during the economic depression (1932–1940) was also associa

Who reads Energy restriction early in life and colon carcinoma risk : Results of the Netherlands Cohort Study after 7.3 years of follow-up?

Author

Miranda J. M. Dirx; Piet A. van den Brandt; R. Alexandra Goldbohm; L. H. Lumey

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0008-543X)

Published

2002

Language

EN

Field

Medicine (Health Sciences)