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Self-assembly of Protein-polymer Conjugates for Drug Delivery by Corey. A. Stevens; Kuljeet Kaur; Harm-Anton Klok is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Self-assembly of Protein-polymer Conjugates for Drug Delivery about?

Protein-polymer conjugates are a class of molecules that combine the stability of polymers with the diversity, specificity, and functionality of biomolecules. These bioconjugates can result in hybrid materials that display properties not found in their individual components and can be particularly relevant for drug delivery applications. Engineering amphiphilicity into these bioconjugate materials can lead to phase separation and the assembly of high-order structures. The assembly, termed self-assembly, of these hierarchical structures entails multiple levels of organization: at each level, new properties emerge, which are, in turn, influenced by lower levels. Here, we provide a critical review of protein-polymer conjugate self-assembly and how these materials can be used for therapeutic applications and drug delivery. In addition, we discuss central bioconjugate design questions and propose future perspectives for the field of protein-polymer conjugate self-assembly.

Who reads Self-assembly of Protein-polymer Conjugates for Drug Delivery?

Author

Corey. A. Stevens; Kuljeet Kaur; Harm-Anton Klok

Publisher

Elsevier BV

Published

2021

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)