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ERAD Mechanisms in Protein Quality Control by animexbouidida is a document available to read on EtoBox.
This review article discusses the mechanisms of substrate processing during ER-associated protein degradation (ERAD), highlighting its role in maintaining proteome integrity by removing misfolded or surplus proteins via the ubiquitin-proteasome system. The authors explore the various independent yet overlapping pathways of ERAD, the role of ER-membrane-bound ubiquitin ligases, and the coordination of specialized factors involved in substrate recognition and degradation. The review emphasizes the physiologic
- Author
- animexbouidida
- Language
- EN