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Can I read Linac-based Radiosurgery or Hypofractionated Stereotactic Radiotherapy in the Treatment of Large Cerebral Arteriovenous Malformations on EtoBox?
Linac-based Radiosurgery or Hypofractionated Stereotactic Radiotherapy in the Treatment of Large Cerebral Arteriovenous Malformations by Angelika Zabel-du Bois; Stefanie Milker-Zabel; Peter Huber; Wolfgang Schlegel; Jürgen Debus is a Medicine article available to read on EtoBox.
What is Linac-based Radiosurgery or Hypofractionated Stereotactic Radiotherapy in the Treatment of Large Cerebral Arteriovenous Malformations about?
## Purpose: We investigate retrospectively clinical outcome after radiosurgery (rs) or hypofractionated stereotactic radiotherapy (hsrt) in patients with large cerebral arteriovenous malformations (avms). ## Methods and materials: This analysis is based on 48 patients with cerebral avm greater than 4 cm treated with hsrt or rs at our institution. fifteen patients received hsrt, with 26 gy median total dose in 4 to 5 fractions, and 33 patients received rs with 17 gy median total dose in 4 to 5 fractions. median target volume was 27 cc in hsrt and 7 cc in rs; median maximum diameter was 6 cm and 5 cm, respectively. seventeen patients experienced intracranial hemorrhage before treatment. median follow-up was 2.6 years. ## Results: The 3-year and 4-year actuarial complete obliteration (co) after hsrt was 17% and 33% and after rs was 47% and 60%, respectively. actuarial co was higher in avms less than 5 cm (66% vs. 37% after 4 years). intracranial hemorrhage after hsrt occurred in 3 of 15 patients after 18 months median, and after rs in 7 of 33 patients after 17 months median. bleeding risk was significantly higher in patients with prior hemorrhage (p < 0.04). preexisting neurologic dys
Who reads Linac-based Radiosurgery or Hypofractionated Stereotactic Radiotherapy in the Treatment of Large Cerebral Arteriovenous Malformations?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Angelika Zabel-du Bois; Stefanie Milker-Zabel; Peter Huber; Wolfgang Schlegel; Jürgen Debus
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)
- Published
- 2006
- Language
- EN
- Field
- Medicine (Health Sciences)