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What is Overview of DNA Vaccines and Efficacy about?

DNA vaccines are simple rings of DNA containing a gene encoding an antigen and a promoter/terminator to make the gene express in mammalian cells. They can generate desired immunity like CTLs, T helper cells, and antibodies, while having advantages of ease of manufacturing, broad population administration, and safety. This review discusses the mechanisms, preclinical and clinical efficacy of DNA vaccines, limitations of first generation vaccines, and promising second-generation developments. DNA vaccines sho

Author

vignesh9489

Language

EN