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Controversy in the allometric application of fixed- versus varying-exponent models: A statistical and mathematical perspective by Huadong Tang; Azher Hussain; Mauricio Leal; Eric Fluhler; Michael Mayersohn is a Chemistry article available to read on EtoBox.

What is Controversy in the allometric application of fixed- versus varying-exponent models: A statistical and mathematical perspective about?

This commentary is a reply to a recent article by Mahmood commenting on the authors' article on the use of fixed-exponent allometry in predicting human clearance. The commentary discusses eight issues that are related to criticisms made in Mahmood's article and examines the controversies (fixed-exponent vs. varying-exponent allometry) from the perspective of statistics and mathematics. The key conclusion is that any allometric method, which is to establish a power function based on a limited number of animal species and to extrapolate the resulting power function to human values (varying-exponent allometry), is infused with fundamental statistical errors.

Who reads Controversy in the allometric application of fixed- versus varying-exponent models: A statistical and mathematical perspective?

Author

Huadong Tang; Azher Hussain; Mauricio Leal; Eric Fluhler; Michael Mayersohn

Publisher

John Wiley and Sons; Elsevier ; Elsevier Inc.; Elsevier BV (ISSN 0022-3549)

Published

2010

Language

EN

Field

Chemistry (Physical Sciences)