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Anti-Biofilm Efficacy of Commonly Used Wound Care Products in In Vitro Settings by Matthew Regulski; Matthew F. Myntti; Garth A. James is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Anti-Biofilm Efficacy of Commonly Used Wound Care Products in In Vitro Settings about?

Considering the prevalence and pathogenicity of biofilms in wounds, this study was designed to evaluate the anti-biofilm capabilities of eight commercially available wound care products using established in vitro assays for biofilms. The products evaluated included dressings with multiple delivery formats for ionic silver including nanocrystalline, gelling fibers, polyurethane (PU) foam, and polymer matrix. Additionally, non-silver-based products including an extracellular polymeric substance (EPS)-dissolving antimicrobial wound gel (BDWG), a collagenase-based debriding ointment and a fish skin-based skin substitute were also evaluated. The products were evaluated on __Staphylococcus aureus__ and __Pseudomonas aeruginosa__ mixed-species biofilms grown using colony drip flow reactor (CDFR) and standard drip flow reactor (DFR) methodologies. Anti-biofilm efficacy was measured by viable plate counts and confocal scanning laser microscopy (CSLM). Four of the eight wound care products tested were efficacious in inhibiting growth of new biofilm when compared with untreated controls. These four products were further evaluated against mature biofilms. BDWG was the only product that achieve

Who reads Anti-Biofilm Efficacy of Commonly Used Wound Care Products in In Vitro Settings?

Author

Matthew Regulski; Matthew F. Myntti; Garth A. James

Publisher

MDPI AG

Published

2023

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)